Hyperkalemia caused by Qingfei Paidu decoction(清肺排毒汤) in a patient with novel coronavirus pneumonia
Department of Pharmacy, the 80th Army Hospital, Shandong Province, Weifang 261021, China; 2Department of Anesthesiology, the 80th Army Hospital, Shandong Province, Weifang 261021, China
Abstract:A 23-year-old male patient received moxifloxacin, recombinant human interferon α-2b for injection, and lopinavir and ritonavir for 7 days for novel coronavirus pneumonia. There was no abnor-malityof serum potassium. Moxifloxacin was stopped, Qingfei Paidu decoction(清肺排毒汤) was given, and then the patient′s serum potassium began to rise. On day 10 after taking the decoction, laboratory tests showed serum potassium 5.7-mmol/L and the patient was diagnosed with hyperkalemia. Insulin injection 4 U diluted to 5% glucose injection 250-ml was given once by IV infusion, and then the serum potassium decreased to 5.0-mmol/L 6 hours later and 4.6-mmol/L 2 days later. After 5 days, the serum potassium rose again and finally to 5.4-mmol/L on day 17 after taking the decoction. Insulin was given once that day and 2 days later once daily according to the previous method. Then the serum potassium decreased and did not rise again. The patient recovered from novel coronavirus pneumonia and was discharged on day 28 after hospitalization.
韩茂之,李莎莎,李静,李宪超,高林林,鹿艳,周子渝. 清肺排毒汤致新型冠状病毒肺炎患者高钾血症[J]. 药物不良反应杂志, 2020, 22(6): 375-376.
Han Maozhi, Li Shasha, Li Jing, Li Xianchao, Gao Linlin, Lu Yan, Zhou Ziyu. Hyperkalemia caused by Qingfei Paidu decoction(清肺排毒汤) in a patient with novel coronavirus pneumonia. Adverse Drug Reactions Journal, 2020, 22(6): 375-376.