2003 Volume 5 Issue 4 Published: 28 August 2003

  

• Select all
  |

调查研究

• Select
  调查研究

  Discussion on the relation between glucocorticoid therapy and secondary infection of SARS Patients

  Zhao Hui;Wang Huizhu

  2003, 5(4): 229-231.

  Abstract ( ) PDF ( )

  Objective:To discuss the relation between glucocorticoid therapy and secondary infection(SI )of SARS patients.Method:Bacterial cultures of blood,urine,stool and sputum of the SARS patients were made in our hospital from26March to24May2003,with statistic analysis of the cases treated with glucocorticoid.Results:There were80individual strains of bacteria isolated from253cases.174patients of them were treated with glucocorticoid.The SI rate was19.0%,while the SI rate of79patients without steroids treatment was7.6%.Statistics showed the significant difference between the two (P<0.01).In severe SARS SI rate was25.9%,for the rest,12.9%.SI rate for patients under the low dose was10.3%and under the high dose,23.3%.Conclusion:The SI rate in SARS patients with glucocorticoid treatment was higher than the rate without it.The severe paitents were much easier infected after steroids because of their suppressed immunity.So the glucocorticoid should be used carefully.
• Select
  调查研究

  Analysis of adverse effects associated with traditional Chinese medicines in77cases

  Jia Yijie;Wang Yuqin;Chang Hongjun;Lin Xiaolan

  2003, 5(4): 231-234.

  Abstract ( ) PDF ( )

  Objective:To investigate adverse effects associated with traditional Chinese medicines for clinical reference.Method:ADR reports of our hospital during1998-2001were analysed.Results:ADRs occured in several organs systems,mainly in skin and its appendages and cardiovascular system.Among more severe reactions were anaphylactic shock,laryngeal edema and dyspnea,probably caused by allergy.Conclusion:Traditional Chinese medicines should be used with more care owing to yearly increase of unwanted reactions.
• Select
  调查研究

  Effects of diammonium glycyrrhizinate on impaired liver function associated with hepatitis B virus mutation to lamivudine

  Wang Guishuang

  2003, 5(4): 234-237.

  Abstract ( ) PDF ( )

  Objective:To observe diammonium glycyrrhizinate for impaired liver function due to lamivudine-induced HBV mutation.Method:40HBV-mutation cases,because of taking lamivudine for over one year,were randomly divided into treatment group and control group,20each.Two groups all received liver-protective remedies,with or without diammonium glycyrrhizinate respectively.Re sults:15cases in treatment group returned to normal liver function and only9in control group did,showing remarkable difference(P<0.05).Conclusion:Diammonium glycyrrhizinate could improve the impaired liver function in patients with lamivudine-induced HBV mutation.