2002 Volume 4 Issue 3 Published: 28 June 2002
  

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    调查研究

  • 调查研究
    Dai Hua;Ye Lika
    2002, 4(3): 150-153.
    Abstract ( ) PDF ( )
    Objective: To investigate the clinical medication in the hospital. Method: 338 cases out of 1283 inpatients in 2000 were randomized for the analysis of prescription patterns. Results: The problems of drug use were presented, such as improper drug combinations, drug incompatibility, irrational use of antibiotics and low level of drug monitoring. Conclusion: The clinical medication practice should be improved.
  • 调查研究
    Xiong Fengzhen
    2002, 4(3): 154-156.
    Abstract ( ) PDF ( )
    Objective: To understand ADR induced by calcium antagonists. Method: Medical literature was retrieved from Chinese Pharmaceutical Abstracts (1992-1999) including 113 articles of 30 journals for ADR occurrence after calcium antagonist treatment. Results: Among 7 calcium antagonists causing ADR in 166 cases nifedipine came first (62 cases, accounting for 37.35% ), followed by flunarizine (51 cases, 30.72%) and nimodipine (20 cases, 12.05%) .ADR of 48 cases (28.92%) located in central nervous system, then 26 cases (15.66% ) in cardiovascular system, and 21 cases (12.65% ) in skin. Except for 2 deaths, 164 cases all recovered after discontinuation of the calcium antagonists and start of the expectant treatment .112 cases ( 67.5 % ) were the elderly over 50. Conclusion: Most of elderly patients suffering from cardio - cerebro - vascular diseases were susceptible to calcium antagonists and should be put in close attention clinically with the adjusted doses.
  • 调查研究
    Gong Lianbing;Zhang XiaOjun;Zhao wei
    2002, 4(3): 156-158.
    Abstract ( ) PDF ( )
    Objective: To analyze the causes of drug rash. Method: The medical records of 50 patients with drug rash were reviewed, which occurred during 1995 - 2000 in the 305th hospital of PLA. Results: The leading sensitizing drugs were penicillin, cefazolin. acetylsalicylic acid and sulfonamides. The traditional Chinese herbal preparations accounted for 20%of ADR . Conclusion: In order to reduce the occurrence of the adverse reactions drugs should be used in a rational way, especially for patients with allergic history.