2001 Volume 3 Issue 4 Published: 28 December 2001
  

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    调查研究

  • 调查研究
    Zhou Ying;Liang Yan;Lu Yunlan
    2001, 3(4): 222-226.
    Abstract ( ) PDF ( )
    Objective: To introduce renal failure by Mutong and the way of its prevention and treatment. Methods: 17 cases of the renal failure by Mutong in our hospital were collected to analyze the clinical characteristics and causes of the adverse reactions. Results: Mutong and the compound Mutong preparations probably caused renal failure after long-term administration and overdosage. Conclusion: Great care could be required of appropriate dosage, treatment course and correct indications in order to assure the efficacy and safe use of the drug.
  • 调查研究
    Wang Rui;Li Naxin;Dong Jingyuan
    2001, 3(4): 226-229.
    Abstract ( ) PDF ( )
    Objective: To investigate the general pattern and characteristics of ADRs to cephalosporins and to guide rational drug use.Methods: 386 cases developing drug adverse reactions to cephalosporins ,reported in Chinese literature in the past 10 years, were analysed.Results:There were 45 cases of type A reaction and 341 cases of type B reaction, mostly with allergic reactions (35.49%)and urinary lesion (29.02%). Serious ADRs amounted to 93 cases, of which,7died. Among cephalosporins, ADRs of cefoperazone (97cases), cefradine (78 cases) and cefazolin (69 cases) accounted for 25.13% , 20.21 % and 17.88% , respectively.Conclusion:Rational use of cephalosporins should be strengthened in the clinical practice in order to prevent and reduce the occurence of ADRs.