2001 Volume 3 Issue 3 Published: 28 September 2001

  

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调查研究

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  调查研究

  Clinical analysis of 12 cases with drug - fever induced by antimicrobial agents

  Tan Cie

  2001, 3(3): 151-154.

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  Objective: To profile the drug- fever due to antimicrobial agents.Methods: In this study 12 hospitalized cases between June 1998 and September 1999 were enrolled who had drug - fever confirmed during antiinfective treatment. Results: More antimicrobials resulted in fever in 12 patients, even more than one drug responsible for the fever in 6 cases. The temperature was back to normal 2-3 days after withdrawal of the drug (9 cases) while it was down pretty soon with another suitable drug substituted (3 cases) .Conclusion: Drug- fever is mainly caused by β- lactam antibiotics like piperacillin sodium. It is important that doctors should bear the ADR of drug - fever in mind to avoid misdiagnosis.
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  ECG changes following risperidone and chlorpromazine

  Zhang Deliang

  2001, 3(3): 154-156.

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  Objective: To determine the effect of risperidone and chlorpromazine on ECG.Methods: ECG of 252 subjects taking risperidone and that of 262 cases with chlorpromazine ingested were in comparison. Results: ECG abnormal rate of the former was 11.12%and the latter 34.74% , showing significantly different from each other. Conclusion: Risperidone is safer than chlorpromazine as for its damage to heart.
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  Adverse reactions of compound danshen injection in 91 cases

  Gong Wenwu

  2001, 3(3): 156-159.

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  Objective: To review ADRs related to compound danshen injection. Methods: Literature survey was based on national medical journals of 1990 - 2000. Results: 123 ADRs of 91 cases taking compound danshen injection were reported showing no differences in the patients' ages and twice more ADRs in male than in female. The occurrence of ADRs was commonly within two hours after injection. As to types of reaction, there were 94 allergic reactions (76.42%) and 29 other reactions (23.58%), the former being skin reactions (46), drug fever (20), anaphylactic shock (18), anaphylactic ashma (6), angioneuroedema (4). Contusion: The ADR is mostly in allergy with its mechanism analysed.