Prediction of tacrolimus exposure and optimization of dosing regimen in patients with liver cirrhosis based on physiologically based pharmacokinetic model

Liu Jing, Yang Dan, Xu Jianwen, Zhou Shuifang, Zhang Desheng, Zhang Shoutian, Guo Guimu

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Adverse Drug Reactions Journal ›› 2025, Vol. 27 ›› Issue (12) : 720-727. DOI: 10.3760/cma.j.cn114015-20250429-00234

Prediction of tacrolimus exposure and optimization of dosing regimen in patients with liver cirrhosis based on physiologically based pharmacokinetic model

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